
One Health has gained more visibility in recent years, due to the complexity of key health issues. In this article, the One Health framework is used to synthesize a governance model capable of going beyond individual health protection strategies. First, the risk category is presented through a discussion of the recent actions supported by the EU for the management of global risks, with respect to the One Health paradigm. Following this, the analysis shifts to “M6 Salute” of the Piano Nazionale di Ripresa e Resilienza (PNRR)1, presenting the measures promoted in a One Health perspective that are oriented at the elderly and frail. Lastly, we highlight the limits and potential of integrated planning, with regard to certain critical issues inherent both to intervention plans on a global scale and to the endemic difficulties of our national health service (NHS).