Thinking about social relations as networks let us better understand all the contradictions and the complexity of modern, advanced society where natural/social and artificial/technological networks can not be considered separately, because of the their strictly interdependence even in the field of health. The article underlines how social relations and everyday experiences are mediated by technology in European and Italian e-Care experiences, regarding to easier access to health information through internet or to interactive systems improving communication between patient and health care system or, finally, developing user friendly technology.