In answer to the changes in the city systems and to the modifications of the society, in the years ’90 it has been possibile to record change of the city policies: to the problem of life qualities of the city, to the infrastructural and services lack, the administrations must face new problema that go from the transformation of the economic structure of the cities, to the participation of new economic operators and to the location of new economic resources for the transformation of the city. The regeneration is born, therefore, not only like action of recovery and improvement of the existing, but also and above all like process of innovation of the participation techniques, of the planning modalities, of the policies, of the forms of cooperation and involvement of the social forces. In the strategies adopted from the cities in order to improve the competitive positioning, important is the role of the "Great Project" in the elaboration of new programs of urban planning and economic regeneration. The city plan, so intended, is not a urbanistic plan, neither an architectonic plan. It is a pragmatic instrument that invest the planning instruments and that it is adapted to the degrees of certainty or uncertainty of the context.
Keywords: Regeneration, negotiation, new tools of government, creative city.