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Ruggiero-Klinghardt Protocol for early diagnosis and treatment of chronic conditions, with particular reference to autism-associated Lyme disease
Journal Title: PNEI REVIEW 
Year:  2017 Issue: Language: Italian 
Pages:  11 Pg. 58-68 FullText PDF:  1077 KB
DOI:  10.3280/PNEI2017-001007
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In this study we describe the Ruggiero-Klinghardt Protocol for diagnosis and treatment of chronic conditions with particular reference to Lyme disease associated with autism. This protocol is based on the application of the Autonomic Response Testing (ART) developed by Dr. Klinghardt and on a precise sequence of diagnostic ultrasonographies and application of therapeutic ultrasounds aimed at identifying pathogens, metabolites, transformed cells or elements of the immune system suggesting the presence of infections associated with with Lyme disease.
Keywords: Autism, Lyme, diagnosis, ecography, autonomic response

  1. Bradstreet JJ, Pacini S e Ruggiero M (2014) A New Methodology of Viewing Extra-Axial Fluid and Cortical Abnormalities in Children with Autism via Transcranial Ultrasonography, Front Hum Neurosci 7:934.
  2. Bradstreet JJ, Ruggiero M e Pacini S (2015) Commentary: Structural and functional features of central nervous system lymphatic vessels, Front Neurosci 9:485.
  3. Bransfield RC, WulfmanJS, Harvey WT, et al. (2008) The association between tick-borne infections, Lyme borreliosis and autism spectrum disorders, Med Hypotheses 70(5):967-974.
  4. Bui L, Aleid A, Alassaf A, et al. (2017) Development of a custom biological scaffold for investigating ultrasound-mediated intracellular delivery, Mater Sci Eng C Mater Biol Appl 70(Pt 1):461-470.
  5. Burbelo PD, Swedo SE, Thurm A, et al. (2013) Lack of serum antibodies against Borrelia burgdorferi in children with autism, Clin Vaccine Immunol 20(7):1092-1093.
  6. Chung MK e LaRiccia PJ (2016) How Do You Deactivate Painful Scars in Your Practice?, Med Acupunct 28(3):162-167.
  7. Embers ME, BartholdSW, Borda JT, et al. (2012) Persistence of Borrelia burgdorferi in rhesus macaques following antibiotic treatment of disseminated infection, PLoS One 7(1):e29914.
  8. Feder HM Jr, Johnson BJ, O’Connell S, et al. (2007) A critical appraisal of “chronic Lyme disease”, N Engl J Med 357(14):1422-1430.
  9. Halperin JJ (2015) Chronic Lyme disease: misconceptions and challenges for patient management, Infect Drug Resist 8:119-128.
  10. Jensen AM, Stevens RJ e Burls AJ (2016) Estimating the accuracy of muscle response testing: two randomised-order blinded studies, BMC Complement Altern Med 16(1):492.
  11. Jia L, Wang Y, Chen J, et al. (2016) Efficacy of focused low-intensity pulsed ultrasound therapy for the management of knee osteoarthritis: a randomized, double blind, placebo-controlled trial, Sci Rep 6:35453.
  12. Kuhn M, Grave S, Bransfield R, et al. (2012) Long term antibiotic therapy may be an effective treatment for children co-morbid with Lyme disease and autism spectrum disorder, Med Hypotheses 78(5):606-615.
  13. Omura Y (1985) A new, simple, non-invasive imaging technique of internal organs and various cancer tissues using extended principles of the “Bi-Digital O-Ring Test” without using expensive imaging instruments or exposing the patient to any undesirable radiation -- Part I, Acupunct Electrother Res 10(4):255-277.
  14. Ruggiero M (2016) Fecal Microbiota Transplantation and the Brain Microbiota in Neurological Diseases, Clin Endosc 49(6):579.
  15. Ruggiero M, Ward E, Smith R, et al. (2014) Oleic Acid, deglycosylated vitamin D-binding protein, nitric oxide: a molecular triad made lethal to cancer, Anticancer Res 34(7):3569-3578.
  16. Schwalb M, Taubmann M, Hines S, et al. (2016) Clinical observation of a novel, complementary, immunotherapeutic approach based on ketogenic diet, chondroitin sulfate, vitaminD3, oleic acid and a fermented milk and colostrums product, Am J Immunol, 12(4):91-98.

, Ruggiero-Klinghardt Protocol for early diagnosis and treatment of chronic conditions, with particular reference to autism-associated Lyme disease in "PNEI REVIEW" 1/2017, pp. 58-68, DOI:10.3280/PNEI2017-001007


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