The immune system effectively protects the subject form multiple microbial dangers and allowed the evolution of the most complex forms of life, ensuring the biological success, the variety of the various forms of life and the adaptation in different ecosystems. Each form of life defends its uniqueness and fights against biological contamination: in humans, the immunological defense systems reach the highest level of complexity and effectiveness. Vaccinations represent one of the most important prevention measures, among those discovered by biomedical research, but must be executed with expertise and timeliness and exclusively on immunocompetent subjects. Vaccines extend the immune memory of the individual and enhance the appropriate future defenses. The maternal-fetal immunological status is however still matter of research and the adoption of multiple vaccination procedures in early stages of the newborn remains questionable and matter of intense research still in progress.
Keywords: Vaccines, Immunological defense, Immunological memory, Neonatal immunity, Antigens, Antibodies.