Asma e ADHD: il possibile ruolo dello stress materno in gravidanza nello sviluppo concomitante di queste patologie

Titolo Rivista PNEI REVIEW
Autori/Curatori Ornella Righi
Anno di pubblicazione 2019 Fascicolo 2019/2 Lingua Italiano
Numero pagine 14 P. 18-31 Dimensione file 139 KB
DOI 10.3280/PNEI2019-002003
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L’ADHD e l’asma sono condizioni prevalenti nell’infanzia, con una patofisiologia complessa che coinvolge l’interazione genetico-ambientale. L’obiettivo di questo articolo è esplorare i fattori che possono aumentare il rischio di sviluppare asma nei bambini con ADHD. I bambini nati prematuramente e/o quelli le cui madri hanno sperimentato stress durante la gravidanza hanno un rischio significativamente maggiore di sviluppare l’asma in concomitanza con ADHD, dimostrando come lo stress prenatale possa influenzare più circuiti fisiobiologici. In questo processo intervengono sia l’attivazione dell’asse ipotalamo-ipofisi-surreni (HPA) sia la mediazione di citochine infiammatorie che determinano cambiamenti funzionali e morfologici del cervello, e alterazioni immunitarie che predispongono ad atopia.;

Keywords:Stress materno, Gravidanza, ADHD, Asma, Infanzia, Citochine infiammatorie.

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Ornella Righi, Asma e ADHD: il possibile ruolo dello stress materno in gravidanza nello sviluppo concomitante di queste patologie in "PNEI REVIEW" 2/2019, pp 18-31, DOI: 10.3280/PNEI2019-002003