The significant spread of IBD (Inflammatory Bowel Disease) or autoimmune gut diseases in Western countries justifies an etiopathogenetic hypothesis according to the urbanization, together with Western diet considered as stressful factors. In some susceptible subjects, due to adverse childhood events (ACEs), these factors could lead to the onset of IBD in adulthood. In animal studies, visceral hypersensitivity has been linked to several ACEs, and in humans IBD can occur in adulthood following ELA that reactivate the disrupted hypothalamic-hypopituitary-adrenal (HPA) axis due to the stressors that occurred during the development phase. This article aims to investigate the role of the HPA axis, the importance of epigenetic transmission of visceral hypersensitivity to the next generation not directly exposed to trauma, and the role of nutrition and yogic breathing as protective factors on an epigenetic level. Being multifactorial diseases, a clinical case is presented with Pnei approach, including nutritional approach, yogic breathing for the control of the perineum and EMDR (Eye Movement Desensitization and Reprocessing) therapy for the elaboration of targets relating to childhood and disease in the present.
Keywords: IBD, RCU, Yoga, Nutrition, EMDR, Pnei.