Are we in front of a process of re-enchantment? By adopting a point of view of social construction, the author proposes a pattern of relationship science-communication, shows in which way the contemporary medicine puts firmer together the couple health-salvation, puts in evidence the ‘post-modern’ perspectives in the religious field, goes back to the analysis of TV communication, and at last propose some paradigmatic cases of enchantment where symbols, material reality, communication, interpretation, indissolubly penetrate each other.