Interactive effects between perceived organizational support and job insecurity: case analysis of a health business - This study explores interactive effects between perceived organizational support and job insecurity on levels of general well-being and work engagement. This case analysis involved 60 employees of a health business out of a population of 154. Using descriptive and inferential statistics, as well as analysis of interaction by means of regressions, it was evidenced that organizational support is positively associated with engagement, as well as partial facets of well-being; moreover job insecurity is negatively partially associated with well-being. The most significant evidence regards an interaction between perceived organizational support and insecurity on engagement levels. Results are discussed on the basis of literature and for the practical implications towards the specific business. Keywords: perceived organizational support, job insecurity, work engagement, wellbeing.