This contribution is based on a thourough thematic analysis of three of the best hopsices selected on national Italian territory, and presents a selection of best practices collected in those facilities through in-depth interviews. «Best practice» indicates an element of experience that has been effective within those facilities and holds the value of a good example for other experiences. More specifically, it denotes an action that, positively experimented, is significant in terms of innovation, efficacy in reaching certain strategic goals (coherence of objectives and results), internal efficiency (good meansends relation), increase in quality, future sustainability, and is replicable and transferable to other contexts.