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NBIC technologies, medicine and law. Considerations in the light of leading international studies
Author/s: Carmelo Guarino 
Year:  2015 Issue: Language: Italian 
Pages:  22 Pg. 93-114 FullText PDF:  266 KB
DOI:  10.3280/SD2015-002004
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The improvement in human lifespan and potential for activity that has been brought about by the ceaseless development of NBIC technologies is certainly not without precedent as a topic for bioethical and legal considerations. These days, however, there is a need to achieve synergy between sciences, philosophies, law and policy-making, so as to generate agreed paradigms and models, as a step towards redefining the limits of what is ethically permissible. Indeed, such limits are notably hard to identify with clarity, as scientific and technological progress is so much faster now than ever before in history. This article uses the method of narrative review to discuss the crucial role now played by emerging technologies in the field of life sciences, in the light of evidence and of the latest studies about the part played by bioethics and law. These are the factors that define the frame of the argument and of the decision-making relative to the context, involving stakeholders and institutions and thus contributing to defining the limits of the need and the extent of what is feasible, recognising that the people are the ultimate aim of every human action
Keywords: Emerging technologies - Medicine - Bioethics - Law

  1. Allhoff, Fritz, Patrick Lin & Daniel Moore, 2010. What Nanotechnology and Why Does It Matter?: From Science to Ethics. Oxford: Wiley-Blackwell.
  2. Bailey, Kenneth [1982]2006. Metodi della ricerca sociale. Tr. it. Bologna: Il Mulino. Bawarski Willie, Elena Chidlowsky, Dhruba Bharali, Shaker Mousa, 2008. Emerging Nanopharmaceuticals. Nanomedicine, Nanotechnology, Biology and Medicine. 4 (4): 273-82.
  3. Bradshaw, Heather, & Ruud ter Meulen, 2010. A Transhumanist Fault Line around Disability: Morphological Freedom and the Obligation to Enhance. Journal of Medicine and Philosophy. Dec.; 35 (6): 670-84.
  4. Beck, Ulrich, [1986]2006. La società del rischio. Verso una seconda modernità. Tr. it. Roma: Carocci.
  5. —, [2008] 2011. Disuguaglianza senza confini. Tr. it. Roma-Bari: Laterza.
  6. Bedau, Mark, John McCaskill, Norman Packard & Steen Rasmussen, 2010. Living Technology: Exploiting Life’s Principles in Technology. Artificial Life. Winter, 16 (1): 89-97.
  7. Besnier, Jean-Michel, 2012. L’homme simplifié. Le syndrome de la touche étoile. Parigi: Fayard.
  8. Bisol, Benedetta, Antonio Carnevale & Federica Lucivero, 2014. Diritti umani, valori e nuove tecnologie. Il caso dell’etica della robotica in Europa. Metodo. International Studies in Phenomenology and Philosophy, 2 (1): 235-52.
  9. Bostrom, Nick, 2005. In Defense of Posthuman Dignity. Bioethics. Vol. 19, (3): 202-14.
  10. Braidotti, Rosi, 2013. The Posthuman. Cambridge: Polity Press.
  11. Califf, Robert, 2004. Defining the Balance of Risk and Benefit in the Era of Genomics and Proteomics. Health Affairs. 23 (1): 77-87.
  12. Carreno, Beatriz, Vincent Magrini, Michelle Becker-Hapak, Saghar Kaabinejadian, Jasreet Hundal, Allegra Petti, Amy Ly, Wen-Rong Lie, William Hildebrand, Mardis Elaine, & Gerald Linette, 2015. A Dendritic Cell Vaccine Increases the Breadth and Diversity of Melanoma Neoantigen-specific T Cells. Science. May 15; 348 (6236): 803-8.
  13. Casonato, Carlo, & Fabio Cembrani, 2011. Il rapporto terapeutico nell’orizzonte del diritto. In Leonardo Lenti, Elisabetta Palermo & Paolo Zatti (a cura di), I diritti in medicina. Milano: Giuffré. Comitato Nazionale di Bioetica, 1992. Informazione e consenso all’atto medico. Presidenza del Consiglio dei Ministri, 18 luglio.
  14. —, 2003. Documento sulle direttive anticipate di trattamento. Presidenza del Consiglio dei Ministri, 18 dicembre.
  15. —, 2004. Il principio di precauzione: profili bioetici, filosofici, giuridici. Presidenza del Consiglio dei Ministri, 18 giugno.
  16. —, 2005. L’alimentazione e l’idratazione di pazienti in stato vegetativo persistente, Presidenza del Consiglio dei Ministri, 30 settembre.
  17. —, 2006a, Nanoscienze e nanotecnologie. Presidenza del Consiglio dei Ministri, 9 giugno.
  18. —, 2006b. Biotecnologie. Presidenza del Consiglio dei Ministri, 9 giugno.
  19. —, 2006c. Etica, salute e nuove tecnologie dell’informazione. Presidenza del Consiglio dei Ministri, 21 aprile.
  20. —, 2006d. Dalla farmacogenetica alla farmacogenomica. Presidenza del Consiglio dei Ministri, 21 aprile. —, 2010a. Neuroscienze ed esperimenti sull’uomo: problemi bioetici. Presidenza del Consiglio dei Ministri, 17 dicembre.
  21. —, 2010b. L’identificazione del corpo umano: profili bioetici della biometria. Presidenza del Consiglio dei Ministri, 26 novembre.
  22. —, 2013a. Diritti umani, etica medica e tecnologie di potenziamento (enhancement) in ambito militare. Presidenza del Consiglio dei Ministri; 22 febbraio.
  23. —, 2013b. Neuroscienze e potenziamento cognitivo farmacologico: profili bioetici. Presidenza del Consiglio dei Ministri, 19 aprile.
  24. Condie, David, 2008. The Modern Era of Orthotics. Prosthetics and Orthotics International. Sept., 32 (3): 313-23.
  25. Corbetta, Piergiorgio, 1999. Metodologie e tecniche della ricerca sociale. Bologna: il Mulino.
  26. Corn, Emanuele, 2013. Il principio di precauzione nel diritto penale. Studio sui limiti all’anticipazione della tutela penale. Torino: Giappichelli.
  27. Donaldson, Ken, Rob Aitken, Lang Tran, Vicki Stone, Rodger Duffin, Gavin Forrest & Andrew Alexander, 2006. Carbon Nanotubes: a Review of their Properties in Relation to Pulmonary Toxicology and Workplace Safety. Toxicological Sciences. July, 92 (1): 5-22.
  28. Ederveen, Antoine, Yuching Lai, Marc van Driel, Tom Gerats & Janny Peters, 2015. Modulating Crossover Positioning by Introducing Large Structural Changes in Chromosomes. BMC Genomics. 16 (1): 89.
  29. Ehrlich, Eugen, [1913]1976. I fondamenti della sociologia del diritto. Tr. it. Milano: Giuffrè.
  30. Engelhardt, Tristram, 1986. The Foundations of Bioethics, New York: Oxford University Press.
  31. —, 2012. Bioethics Critically Reconsidered: Having Second Thoughts. Dordrecht: Springer.
  32. Ewald, François, & Stephen Utz, 2002. The Return of Descartes’s Malicious Demon: An Outline of a Philosophy of Precaution. In Tom Baker & Jonathan Simon (a cura di), Embracing Risk. Chicago: University of Chicago Press.
  33. Febbrajo, Alberto, 2013. Sociologia del diritto. Bologna: il Mulino.
  34. Fukuyama, Francis, & Franco Furger, 2007. Beyond Bioethics. A Proposal for Modernizing the Regulation of Human Biotechnologies. Washington, DC: Paul H. Nitze School Advanced International Studies, Johns Hopkins University.
  35. Fumagalli, Manuela, Sara Marceglia, Filippo Cogiamanian, Gianluca Ardolino, Marta Picascia, Sergio Barbieri, Gabriella Pravettoni, Claudio Pacchetti & Alberto Priori, 2015. Ethical Safety of Deep Brain Stimulation: A Study on Moral Decision-making in Parkinson’s Disease. Parkinsonism & Related Disorders. July, 21 (7): 709-16.
  36. Gordijn, Bert, & Ruth Chadwick, 2008. Medical Enhancement and Posthumanity. Dordrecht: Springer Verlag Gmbh.
  37. Huxley, Julian, 1957. New Bottles for New Wine. Essay by Julian Huxley. London: Chatto & Windus.
  38. Ihde, Don, 1990. Technology and the Lifeworld: from Garden to Earth. Bloomington-Indianapolis: Indiana University Press. Issler, Orna, & Aron Chen, 2015 Determining the Role of MicroRNAs in Psychiatric Disorders. Nature Reviews Neuroscience. Apr., 16 (4): 201-12.
  39. Kastenhofer, Karen, & Jan Schmidt, 2011. Technoscientia est Potentia?: Contemplative, Interventionist, Constructionist and Creationist Idea(l)s in (Techno) science. Poiesis & Praxis. Dec., 8 (2-3): 125-49.
  40. Kimmelman, Jonathan, 2012. Beyond Human Subjects: Risk, Ethics, and Clinical Development of Nanomedicines. Journal of Law, Medicine & Ethics. Winter, 40 (4): 841-47.
  41. Lecellier, Charles-Henri, 2011. The Democratic Side of Science-fiction. Médecine/Sciences (Paris). Apr., 27 (4): 433-38.
  42. Lynch, Zack, 2004. Neurotechnology and Society (2010-2060). Annals of the New York Academy of Sciences. May, 1013: 229-33.
  43. Mallardi, Vito, 2005. The Origin of Informed Consent. Acta Otorhinolaryngologica Italica. Oct., 25 (5): 312-27.
  44. Maojo, Víctor, Fernando Martin-Sanchez, Casimir Kulikowski, Alfonso Rodriguez-Paton & Martin Fritts, 2010. Nanoinformatics and DNA-based Computing: Catalyzing Nanomedicine. Pediatric Research. 67 (5): 481-89.
  45. Marchant, Gary, & Rachel Lindor, 2012. Prudent Precaution in Clinical Trials of Nanomedicines. Journal of Law, Medicine & Ethics. Winter, 40 (4): 831-40.
  46. Marchesini, Roberto, 2009. Il tramonto dell’uomo. La prospettiva post-umanista. Bari: Edizioni Dedalo.
  47. Meyerson, Denise, 2013. Innovative Surgery and the Precautionary Principle. Journal of Medicine and Philosophy. Dec., 38 (6): 605-24.
  48. Morin, Edgar, 2005. Introduction à la pensée complexe. Paris: Seuil.
  49. Mushiaki, Shigeru, 2011. Neuroscience and Nanotechnologies in Japan – Beyond the Hope and Hype of Converging Technologies. Journal International de Bioéthique. Mar.-June, 22 (1): 91-97, 210-11.
  50. —, 2013. Ethica ex Machina: Issues in Roboethics. Journal International de Bioéthique. Dec., 24 (4): 17-26, 176-177.
  51. Neresini, Federico, 2006. Bioetica, medicina e società. In Massimiliano Bucchi (a cura di), Sociologia della salute. Roma: Carocci.
  52. Nezhmetdinova, Farida, 2013. Global Challenges and Globalization of Bioethics. Croatian Medical Journal. Feb., 54 (1): 83-85.
  53. Oliva-Sánchez Francisco, Marcos Jafif-Cojab, Isaac Akkad-Schaffer & Esteban Waliszewski-Zamorano, 2013. Equity, Public Health and Genomics: the Legal, Social and Biotechnology Challenge in México. Gaceta Médica de México. Sep-Oct; 149 (5): 562-68.
  54. Pagliaro, Luigi, 2006. Medicina basata sulle evidenze e centrata sul paziente. Un dizionario di termini clinici. Roma: Il Pensiero Scientifico.
  55. Polizzi, Gaspare, 2011. Vite degne di essere vissute. Note sulla prospettiva postumana. Alfabeta. 8: 32.
  56. Pushpa, Bhargava, 2006. The Social, Moral, Ethical, Legal and Political Implications of Today’s Biological Technologies: An Indian Point of View. Biotechnology Journal. Jan., 1; (1): 34-46.
  57. Reich, Warren, 1978. Encyclopedia of Bioethics. New York: Free Press. Roco, Mihail, William Bainbridge, Bruce Tonn & George Whitesides, 2013. Convergence of Knowledge, Technology and Society. Beyond Convergence of Nano-Bio-Info-Cognitive technologies. Dordrecht: Springer.
  58. Roco, Mihail, & William Bainbridge, 2003. Converging Technologies for Improving Human Performance. Nanotechnology, Biotechnology, Information Technology and Cognitive science. Edited by National Science Foundation. Dordrecht: Kluwer.
  59. Rodotà, Stefano, 2012. Il diritto di avere diritti. Roma-Bari: Laterza.
  60. Rothwell, Peter, 2005. External Validity of Randomised Controlled Trials: to Whom Do the Results of this Trial Apply? Lancet. Jan., 365 (9453): 82-93.
  61. Sala, Valeria, Lorenzo Moja, Ivan Moschetti, Sabrina Bidoli, Vanna Pistotti & Alessandro Liberati, 2006. Revisioni sistematiche. Centro Cochrane Italiano. In
  62. Saraceno, Chiara, 2015. Quando le leggi vanno piano accelerano i magistrati. La Repubblica. 20 gennaio.
  63. Sententia, Wrye, 2004. Neuroethical Considerations: Cognitive Liberty and Converging Technologies for Improving Human Cognition. Annals of the New York Academy of Sciences. May, 1013: 221-28.
  64. Spagnolo, Antonio, & Viviana Daloiso, 2009. Outlining Ethical Issues in Nanotechnologies.
  65. Bioethics. 23 (7): 394-402.
  66. Swierstra, Tsjalling, Marianne Boenink, Bart Walhout & Rinie van Est, 2009. Converging Technologies, Shifting Boundaries. Nanoethics. Dec; 3 (3): 213-16.
  67. Timmermans, Job, Yinghuan Zhao & Jeroen van den Hoven, 2011. Ethics and Nanopharmacy: Value Sensitive Design of New Drugs. Nanoethics. Dec., 5 (3): 269-83.
  68. Tononi, Giulio, 2012. Phi: a Voyage from the Brain to the Soul. New York: Pantheon Books.
  69. Treves, Renato, [1987]2002. Sociologia del diritto. Origini, ricerche, problemi. Torino: Einaudi.
  70. Verbeek, Peter-Paul, 2005. What Things Do: Philosophical Reflections on Technology, Agency and Design. Penn State: Penn State University Press.
  71. Van Est, Rinie, & Dirk Stemerding, 2013. Governance Strategies for Living Technologies: Bridging the Gap between Stimulating and Regulating Technoscience. Artificial Life. Summer-Fall, 19 (3-4): 437-50.
  72. Van Hilvoorde, Ivo, & Laurens Landeweerd, 2010. Enhancing Disabilities: Transhumanism under the Veil of Inclusion? Disability and Rehabilitation. 32 (26): 2222-27.
  73. Weston, Andrea, & Leroy Hood, 2004. Systems Biology, Proteomics, and the Future of Health Care: toward Predictive, Preventative, and Personalized Medicine. Introduction: paradigm changes in health care. Journal of Proteome Research. (3): 179-96.
  74. Wolbring, Gregor, 2004. Solutions Follow Perceptions: NBIC and the Concept of Health, Medicine, Disability and Disease. Alberta Health Law Review. 12 (3): 41-46. —, 2006. Emerging Technologies (Nano, Bio, Info, Cogno) and the Changing Concepts of Health and Disability/Impairment: a New Challenge for Health Policy, Research and Care. Journal of Health and Development (India) 2 (1 & 2): 19-37.
  75. Wolff, Jan, 2014. The Precautionary Attitude: Asking Preliminary Questions. Hastings Center Report. Nov., 44 Suppl. 5: 27-28.
  76. Wu Bin, Lu Han, Bo-Min Sun, Xiao-Wu Hu & Xiao-Ping Wang, 2014. Influence of Deep Brain Stimulation of the Subthalamic Nucleus on Cognitive Function in patients with Parkinson’s disease. Neuroscience Bulletin. Feb., 30 (1): 153-61.

Carmelo Guarino, NBIC technologies, medicine and law. Considerations in the light of leading international studies in "SOCIOLOGIA DEL DIRITTO " 2/2015, pp. 93-114, DOI:10.3280/SD2015-002004


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