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Autismo ed infi ammazione
Titolo Rivista: PNEI REVIEW 
Autori/Curatori: Dario Siniscalco 
Anno di pubblicazione:  2017 Fascicolo: 1 Lingua: Italiano 
Numero pagine:  8 P. 33-40 Dimensione file:  1093 KB
DOI:  10.3280/PNEI2017-001004
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L’autismo ed i disturbi dello spettro autistico (DSA) comprendono patologie complesse dello sviluppo neurologico caratterizzati da difetti cognitivi, dell’interazione sociale e della comunicazione, del linguaggio e problemi comportamentali. L’interazione tra fattori genetici ed ambientali è alla base di tale patologia, anche se la patogenesi non è ancora del tutto chiara. Una serie di eventi biochimici sono associati con l’autismo, così come disfunzioni immunitarie e problemi gastrointestinali. La componente infiammatoria ed immuno-mediata riveste particolare importanza nello sviluppo di questi disordini. Recenti evidenze sottolineano come il sistema molecolare degli endocannabinoidi sia alla base della disfunzione immunitaria ed infiammatoria.


Keywords: Autismo, endocannabinoidi, neuro-immunomodulazione

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Dario Siniscalco, in "PNEI REVIEW" 1/2017, pp. 33-40, DOI:10.3280/PNEI2017-001004

   

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