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Lavoro di cura e innovazione tecnoscientifica: il caso della medicina personalizzata
Journal Title: SALUTE E SOCIETÀ 
Author/s: Stefano Crabu 
Year:  2017 Issue: 3-Suppl. Language: Italian 
Pages:  17 Pg. 197-213 FullText PDF:  106 KB
DOI:  10.3280/SES2017-SU3013
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In contemporary biomedicine, care practices are increasingly interlaced with research and development activities, leading to the emergence of new biomedical domains, such as personalized medicine. Personalized medicine involves the shaping of unprecedented relationships between clinical practice and technoscientific innovation processes, which need to be explored in their social and technological dimensions. In this article, based on ethnographic research carried out within an institute of care and research in Northern Italy, it will be analysed the reconfiguration of medical practice and health professions due to the increasing adoption of organizational strategies in support of the circulation of knowledge, biological materials and technologies between scientific laboratories and care settings. From the analytical point of view, a special attention it will be paid to the organizational arrangements performed by physicians and scientist in order to support the dialogue between research laboratories and care contexts, in which personalised medicine is shaped.
Keywords: Translational biomedicine; personalised medicine; oncology; biomarkers; clinical and experimental technomimicry; ethnography.

  1. Abadie R. (2010). The Professional Guinea Pig: Big Pharma and the Risky World of Human Subjects. Durham: Duke University Press.
  2. Abu El-Haj N. (2007). The genetic reinscription of race. Annual Review of Anthropology, 36: 283-300.
  3. Allsop J., Mulcahy L. (1996). Regulating Medical Work: Formal and Informal Controls. Buckingham: Open University Press.
  4. Bruni A. (2008). La medicina come ingegneria dell’eterogeneo e pratica sociomateriale. Rassegna Italiana di Sociologia, 49: 451-476., 10.1423/2767DOI: 10.1423/2767
  5. Bruni A., Pinch T., Schubert C. (2013). Technologically Dense Environments: What For? What Next?. Tecnoscienza: Italian Journal of Science & Technolo-gy Studies, 4: 51-72.
  6. Butler D. (2008). Translational research: Crossing the valley of death. Nature, 453: 840-842., 10.1038/453840DOI: 10.1038/453840
  7. Clarke A.E., Mamo L., Fosket J., Fishman J.R. e Shim J.K., a cura di (2010). Bio-medicalization: Technoscience, Health, and Illness in the U.S. Durham: Duke University Press.
  8. Crabu S. (2014). Allineare umani, tecnologie e saperi: il lavoro infrastrutturante negli ambienti tecnologicamente densi. Studi Organizzativi, 16(1): 50-72., 10.3280/SO2014-00100DOI: 10.3280/SO2014-00100
  9. Crabu S. (2016). Translational biomedicine in action: Constructing biomarkers across laboratory and benchside. Social Theory & Health, 14: 312–331.
  10. Crabu S. (2017). Dalla molecola al paziente. La biomedicina nella società con-temporanea. Bologna: Il Mulino.
  11. Douglas C.M.W. (2012). Bio-objectification of Clinical Research Patients: Impacts on the Stabilization of New Medical Technologies. In: Vermeulen N., Tamminen S., Webster A., editors, Bio-Objects. Life in the 21st Century. London: Ashgate.
  12. Fortun M. (2002). The Human Genome Project: Past, Present, and Future Anterior. In: Garland E.A. e MacLeod R.M., editors, Science, History, and Social Activism: A Tribute to Everett Mendelsohn. Dordecht: Kluwer Academic Publishers.
  13. Fosket J.F. (2004). Constructing ‘high risk’ women: The development and standardization of a breast cancer risk assessment tool. Science, Technology & Hu-man Values, 29: 291-323., 10.1177/016224390426496DOI: 10.1177/016224390426496
  14. Foucault M. (1963). Naissance de la clinique. Une archéologie du regard medical. Paris: Presses Universitaires de France (trad. it.: Nascita della clinica: una archeologia dello sguardo medico. Torino: Einaudi, 1998).
  15. Fox E.K. (2000). The Century of the Gene. Massachusetts: Harvard University Press (trad. it.: Il secolo del gene. Milano: Garzanti, 2001).
  16. Fujimura J.H. (1995). Ecologies of Action: Recombining Genes, Molecularizing Cancer, and Transforming Biology. In: Star S.L., editor, Ecologies of Knowledge: Work and Politics in Science and Technology. Albany: State Uni-versity of New York Press.
  17. Lewis J., Hughes J., Atkinson P. (2014). Relocation, realignment and standardisation: Circuits of translation in Huntington’s disease. Social Theory & Health, 12: 396-415.
  18. Lock M. (2007). The future is now: locating biomarkers for dementia. In: Burri, R.V., Dumit, J., editors, Biomedicine as Culture: Instrumental Practices, Technoscientific Knowledge, and New Modes of Life. New York: Routledge.
  19. Keating P., Cambrosio A. (2003). Biomedical Platforms: Realigning the Normal and the Pathological in Late-Twentieth-Century Medicine. Cambridge: MIT Press.
  20. Keating P., Cambrosio A., Nelson N.C. (2016). “Triple negative breast cancer”: Translational research and the (re) assembling of diseases in post-genomic medicine. Studies in History and Philosophy of Biological and Biomedical Sciences, 59: 20-34.
  21. Kohli-Laven N., Bourret P., Keating P., Cambrosio A. (2011). Cancer clinical trials in the era of genomic signatures: biomedical innovation, clinical utility, and regulatory-scientific hybrids. Social Studies of Science, 41: 487-513., 10.1177/030631271139874DOI: 10.1177/030631271139874
  22. Orlikowski W.J. (2007). Sociomaterial practices: Exploring Technology at Work. Organization Studies, 28: 1435-1448., 10.1177/017084060708113DOI: 10.1177/017084060708113
  23. Rose N. (2007). The Politics of Life Itself. Biomedicine, Power, and Subjectivity in the Twenty-First Century. Princeton: Princeton University Press (trad. it.: La politica della vita. Biomedicina, potere e soggettività nel XXI secolo. Torino: Einaudi, 2008).
  24. Rose N. (2013). The human sciences in a biological age. Theory, Culture & Society, 30: 3-34., 10.1177/026327641245656DOI: 10.1177/026327641245656
  25. Suchman L. (2000). Organizing Alignment: A Case of Bridge-Building. Organization, 7: 311-327., 10.1177/13505084007200DOI: 10.1177/13505084007200
  26. Sulik A.G. (2009). Managing biomedical uncertainty: The technoscientific illness identity. Sociology of Health & Illness, 31: 1059-1076.
  27. Torre L.A., Siegel R.L., Ward E.M., Jemal A. (2016). Global Cancer Incidence and Mortality Rates and Trends. An Update. Cancer Epidemiology, Biomarkers & Prevention, 25: 16-27., 10.1158/1055-9965.EPI-15-057DOI: 10.1158/1055-9965.EPI-15-057
  28. Turrini M. (2011). Introduzione. Biotecnologie, salute e lavoro clinico. In: Turrini M., a cura di, Biocapitale. Vita e corpi nell’era del controllo biotecnologico. Verona: Ombre Corte.
  29. Tutton R. (2012). Personalizing medicine: Futures present and past. Social Science & Medicine, 75: 1721–1728.
  30. van den Hoonaard D.K. (2009). Moving toward a three-way intersection in translational research: a sociological perspective. Qualitative Health Research, 19: 1783-1787., 10.1177/104973230935499DOI: 10.1177/104973230935499
  31. Wainwright S.P., Williams C., Michael M., Farsides B., Cribb A. (2006). From bench to bedside? Biomedical scientists’ expectations of stem cell science as future therapy for diabetes. Social Science & Medicine, 63: 2052–2064.

Stefano Crabu, in "SALUTE E SOCIETÀ" 3-Suppl./2017, pp. 197-213, DOI:10.3280/SES2017-SU3013

   

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