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Neurobiologia delle relazioni interpersonali fattori di rischio di malattia
Titolo Rivista: MALTRATTAMENTO E ABUSO ALL’INFANZIA 
Autori/Curatori: Maria Cristina Verrocchio, Daniela Marchetti, Piero Porcelli 
Anno di pubblicazione:  2018 Fascicolo: Lingua: Italiano 
Numero pagine:  18 P. 13-30 Dimensione file:  245 KB
DOI:  10.3280/MAL2018-003002
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Le relazioni precoci hanno un effetto strutturante su molteplici aspetti della salute mentale e fisica. Scopo di questo lavoro è analizzare le evidenze derivanti da studi sperimentali, osservazionali ed epidemiologici del rapporto fra relazioni infantili negative e fattori di rischio di malattie mediche in età adulta, esaminando in modo particolare i meccanismi epigenetici (metilazione del DNA e lunghezza dei telomeri). L’analisi della letteratura indica che le esperienze relazionali precoci hanno effetti negativi sulla salute fisica per tutta la vita e che il meccanismo più probabile è il condizionamento della riprogrammazione biologica attraverso le modificazioni epigenetiche e le conseguenziali interazioni fra SNC e sistema immunitario.


Keywords: Attaccamento, funzionamento cerebrale, sistema immunitario, epigenetica.

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Maria Cristina Verrocchio, Daniela Marchetti, Piero Porcelli, in "MALTRATTAMENTO E ABUSO ALL’INFANZIA" 3/2018, pp. 13-30, DOI:10.3280/MAL2018-003002

   

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