Institutional reforms and legislative interventions, having affected the healthcare system for years, seem to confer to the middle management an important role in managing organisational change. From the stories collected through research carried out among learners and ex-learners of the Master in Management and Innovation at Sapienza University of Rome, it has emerged the need for them to develop transversal skills indispensable for performing their role as medi-ators of top-down organisational innovations. Concerning digitalisation processes, we have collected both stories of resistance to the use of ICT and also the request for a participatory and integrated design of technological innovations. Uncertainties and cultural resistances caused by these changes fragment careers of professional women and men who narrate how they put in play different practices and skills in building their own paths and, for women only, in reconciling them with their care activity.
Keywords: Transversal skills; middle management; eHealth; technological innovation; work-life balance; careers.