This paper provides my thinking on several possible new directions in empirical migration research, as well as refinements of old directions. The focus is mainly on developed countries, but given the availability of appropriate data for less-developed countries, many of the studies could fruitfully be applied to such countries. The essay is organized around the six major questions addressed in studies of migration: (1) How many migrate? (2) Who migrates? (3) Why do they migrate? (4) Where do the migrants come from and where do they go? (5) When do they migrate? (6) What are the consequences of the migration?